The combination of trimethoprim and sulfamethoxazole acts synergistic and usually bactericidal against many Gram-positive and Gram-negative bacteria like E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. Both compounds affect bacterial purine synthesis in a different way, as a result, of which a double blockade is accomplished.
per ml
200 mg sulfamethoxazole
40 mg trimethoprim
5 mg lidocaine
slowly iv, im or intramammary. General 1 ml per 15 kg bodyweight daily during 5 consecutive days
100ml vial
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